Polynucleotide Therapy
Next-generation DNA repair therapy that regenerates skin at a cellular level — for lasting quality improvement from within.
What Are Polynucleotides?
Polynucleotides (PDRN) are purified DNA fragments derived from salmon or trout DNA. When injected, they stimulate cellular repair, boost collagen synthesis, and enhance skin regeneration at a fundamental level.
Treatment Areas
Under Eyes & Dark Circles
Reduces hollowing, dark circles, and crepey skin around the delicate eye area.
Face & Neck
Improves overall skin quality, texture, and firmness for natural rejuvenation.
Scalp & Hair
Stimulates hair follicle regeneration and promotes natural hair growth.
Hands & Décolletage
Addresses thinning skin, age spots, and loss of elasticity in exposed areas.
Am I Suitable?
May Be Suitable
- • Dark circles and under-eye hollowing
- • Fine lines and skin laxity
- • Dull, tired-looking skin
- • Hair thinning or early hair loss
- • Sun-damaged or ageing skin
May Not Be Suitable
- • Known fish allergy (salmon-derived PDRN)
- • Active skin infections
- • Pregnancy or breastfeeding
- • Autoimmune conditions
Before & After




Individual results vary. Images show real patients treated at our Harley Street clinic.
Why CosmeDocs?
- Doctor-led — all treatments by GMC-registered doctors
- Harley Street, London — established 2007
- Over 1 million treatments performed
- Advanced regenerative medicine expertise
- Personalised treatment plans
- Our aesthetics is invisible art
Frequently Asked Questions
At a Glance
Duration
20–30 minutes
Results last
6–12 months
Recovery
Minimal downtime
Product
PDRN / Polynucleotides
Treatment Pricing
Personalised plan after consultation
Laura K.
"The polynucleotide treatment has genuinely transformed my skin texture. It looks healthier and more radiant than it has in years."
More real experiencesPolynucleotide Treatment London — Advanced DNA Repair Therapy at Harley Street
CosmeDocs offers doctor-led polynucleotide treatments for skin regeneration, under-eye rejuvenation, and hair restoration at our Harley Street clinic. Polynucleotide therapy uses purified DNA fragments (PDRN) to stimulate cellular repair, boost collagen synthesis, and enhance skin quality from within. Results develop progressively over months. Our aesthetics is invisible art — bold, natural, always your way.